Supplement Guide

I’ve created this guide to help you choose the best supplements for your particular needs. Not all supplements are created equal; the manufacturing process, the specific form of the nutrient (i.e. natural or synthetic, chelates, ascorbates, etc.), the delivery system (i.e. liposomal, transdermal, etc.), and the way nutrients are combined and proportioned are all critical variables in determining the quality and suitability of a supplement.

As a working clinician, part of my job is to continue researching the best supplements for each particular condition or therapeutic application, so I can deliver the best possible care to my patients. In this guide, I’ve listed many of the same products that I use in my practice with patients. I have also created bundles of these products for each health condition I cover in the book and the bonus chapters on the website. I’ve made both the individual products and the bundles available in my online store. That way you will have access to same high quality products I prescribe to my patients, and you can rest assured that you’re taking the proper form of each nutrient with the optimal delivery system.

Remember to check with your physician or health care provider before beginning a supplementation protocol.

Two categories of supplementation

I separate supplementation into two categories: maintenance, and therapeutic. Maintenance supplementation involves supplementing with selected micronutrients that are difficult to obtain even in the context of a nutrient-dense Paleo diet. Supplements in this category are generally taken in small doses, indefinitely. Therapeutic supplementation involves using supplements for a specific purpose for a specific period of time. For example, you might take melatonin on an overseas trip that involves moving across several time zones, or you might be take vitamin C if you feel a cold coming on.

Addressing common challenges and maximizing chances for success

After working with hundreds of patients, and hearing from thousands of blog readers and podcast listeners, I realized that a large majority of people have three problem areas:

• Digestive distress
• Low energy and sugar cravings
• Poor detox capacity (often manifests as acne, hormone imbalance, depression or anxiety, or cognitive problems)

When I encounter a patient like this in my private practice, there are certain steps I take to smooth their transition to Paleo and increase their chances of success. One of those steps is providing supplemental nutrients that many people tend to be deficient in. Another is prescribing supplements for therapeutic purposes, depending on the particular condition the patient has.

While the best results will always be obtained by working with a skilled practitioner, I recognize that this isn’t always possible. I’ve provided some general guidance below for those that are not able to work with a practitioner.

Maintenance Supplements

VITAMINS A & D

Suggested supplement: Extra Virgin Cod Liver Oil (EVCLO). The highest quality cod liver oil currently on the market.
Dosage: 1 teaspoon per day.

VITAMIN K2

Suggested supplement: Liquid K2 from Thorne. Pure vitamin K2 without K1.
Dosage: 1 mg/d.

MAGNESIUM

Suggested supplement: Magnesium Glycinate from Douglas Laboratories. A highly absorbable form of magnesium.
Dosage: 250–350 mg/d

SELENIUM

Suggested supplement: Selenium from Emerson Ecologics
Dosage: 200 mcg/d. Do not exceed 400 mcg/d of selenium.

IODINE

Suggested supplement: Kelp tablets from NOW
Dosage: 325 mcg/d. Note: exercise caution if you have autoimmune thyroid disease, and make sure you are also taking selenium while supplementing with iodine.

VITAMIN C

Suggested supplement: Liposomal C from Seeking Health. A liposomal form of vitamin C that is more bioavailable than standard vitamin C preparations.
Dosage: 1 tsp per day on an empty stomach.

Therapeutic Supplementation

WEIGHT LOSS

General recommendations:

• L-carnitine: 150–250 mg/d
• EGCG (green tea extract): 100–300 mg/d
• Chromium: 150–250 mcg/d (as chromium chelate)
• Magnesium: 200–400 mg/d (as glycinate or malate)
• Probiotics and prebiotics

Chris’s Preferred Products & Dosages:

• Metabolic Synergy by Designs for Health. Helps support healthy glucose and insulin levels. Dosage is six capsules per day, two with each meal, or as directed by your healthcare practitioner.
• GlucoSupreme by Designs for Health. Supports healthy blood sugar with the use of cinnamon, corosolic acid from banaba, isoflavones from kudzu, and ginsenosides from ginseng. Dosage is two capsules two times daily with meals, or as directed by your healthcare practitioner.
• Magnesium Glycinate by Douglas Laboratories. A highly absorbable form of magnesium. Take 1 capsule 3 times a day with meals.
• Prescript Assist from Magnetic Clay. Soil-based organisms combined with a fulvic-acid-based prebiotic. Dosage is 1 capsule a day for the first 7 days, followed by 2 capsules a day for 30–90 days (until desired results are obtained), and then 1 capsule a day thereafter.
• Prebiogen from ChrisKresser.com. A synergistic blend of arabinogalactan, beta-glucan, inulin, and oligofructose. Start with 1/16 (half of 1/8 teaspoon) per day mixed in a small amount of water or put directly in your mouth, and build up very slowly to one full scoop per day, with or without food. If you experience a significant increase in gas and bloating that doesn’t resolve after 2-3 days, reduce the dose.

Suggested supplement bundle:

I’ve created a discounted bundle of the supplements above that I recommend for weight loss, which you can learn more about and purchase here.

HIGH CHOLESTEROL AND HEART DISEASE

Note: supplementation for high cholesterol and heart disease depends on several different factors and must be tailored to your particular situation to be most effective. For more information on which supplements are right for you and why, please see my online educational program called the High Cholesterol Action Plan. Check with your physician before beginning any of these supplements, especially if you have pre-existing heart disease.

General Recommendations:

• Tocotrienols: 200 mg/d in delta and gamma form, containing <40 mg of tocopherols.
• Pantethine: 900 mg/d, either as 450 mg twice a day or 300 mg three times a day, with food.
• High-potency fish oil: 1 gram per day if you don’t have insulin resistance or metabolic syndrome; 2–3 grams per day if you do.
• Probiotics: soil-based organisms preferred. Dose varies depending on product.
• Prebiotics: dose varies depending on product.
• Glutathione: 450 mg/d in liposomal form. Recommended if signs of inflammation or oxidative damage are present.
• Curcumin: 600 mg/d, in water-soluble, nanoparticle form. Recommended if signs of inflammation or oxidative damage are present.
• CoQ10: 100–200 mg/d in ubiquinol form. Recommended if currently taking statins, or struggling with adverse effects caused by previous statin use.
• Red yeast rice extract: 2,400 mg/d. Brand selection (see below) is critical to avoid mycotoxins and ensure consistency of active ingredient.

Chris’s Preferred Products & Dosages:

• Pantethine from Jarrow Formulas. A high-potency form of pantothenic acid. Take 1 capsule twice daily with food.
• Annatto Tocotrienols from Designs for Health. Delta- and gamma-tocotrienols in the annato form. Take 1 capsule in the evening with food.
• Vitality Ultra-Pure Fish Oil. The highest-potency fish oil on the market, with 992 mg of absorbed omega-3s per 1,000 mg capsule. Take 1 capsule per day if you don’t have insulin resistance or metabolic syndrome; 2–3 capsules per day if you do.
• Prescript Assist from Magnetic Clay. Soil-based organisms combined with a fulvic-acid-based prebiotic. Dosage is 1 capsule a day for the first 7 days, followed by 2 capsules a day for 30–90 days (until desired results are obtained), and then 1 capsule a day thereafter.
• Prebiogen from Chris Kresser. A synergistic blend of arabinogalactan, beta-glucan, inulin, and oligofructose. Take 1 capsule a day.
• Liposomal Glutathione from Seeking Health. A liposomal form of glutathione (GSH), which is highly absorbable and effective. Take one teaspoon per day on an empty stomach.
• Longvida Optimized Curcumin from VRP. A highly bioavailable form of curcumin that is better absorbed than standard curcumin preparations. Take 1 twice a day on an empty stomach.
• Ubiquinol QH Absorb from Jarrow Formulas. A highly absorbable form of CoQ10 that is used in many scientific studies. Take 200 mg once a day with food.
• Choleast 900 from Thorne. Take 1 capsule three times a day with food.

Suggested supplement bundle:

I’ve created several discounted bundles of the supplements above for heart disease, depending on your level of risk. (To determine your level of risk, please see the High Cholesterol Action Plan.) You can learn more about the bundles and purchase them here.

HIGH BLOOD PRESSURE

General Recommendations:

• CoQ10: 100–225 mg per day as ubiquinol (Kaneka form preferred).
• Garlic extract: a dose that provides 10,000 IU of allicin per day; make sure it is enteric coated.
• Vitamin C: 1 tsp per day, on an empty stomach, in liposomal form.
• Magnesium: 500–700 mg per day in glycinate form.
• Potassium (optional): 2,000–3,000 mg per day in gluconate form. This is only necessary if you’re not eating high-potassium foods like starchy plants (e.g. potatoes, sweet potatoes, plantains), fish and bananas.

Chris’s Preferred Products & Dosages:

• Ubiquinol QH Absorb from Jarrow Formulas. A highly absorbable form of CoQ10 that is used in many scientific studies. Take 200 mg per day with food.
• Garlicin from Nature’s Way. A high-potency form of garlic extract with 6,000 units of allicin per capsule. Take 1 capsule twice daily with food.
• Liposomal  Vitamin C from Seeking Health. A liposomal form of vitamin C. Take 1 tsp per day on an empty stomach.
• Magnesium Glycinate from Douglas Laboratories. 5–7 capsules per day in divided doses, taken with food.

Suggested supplement bundle:

I’ve created a discounted bundle of the supplements above that I recommend for weight loss, which you can learn more about and purchase here.

DIGESTIVE DISORDERS

General Recommendations:

• Hydrochloric acid (HCL): see the HCL Protocol Cheatsheet for dosing instructions. HCL should always be taken with either acid stable protease or pepsin.
• Digestive enzymes and liver/gall bladder support: these include proteases and peptidases to break down proteins; lipases to break down fats; carbohydrases to break down carbohydrates; and nutrients to stimulate proper bile synthesis and metabolism. Dosage will vary depending on the product.
• Nutrients to heal and seal the gut barrier: these include L-glutamine, MSM, quercetin, N-acetyl glucosamine, mucin, DGL, slippery elm, marshmallow and cat’s claw. Dosage will depend on the specific formula.
• Probiotics: I recommend soil-based organisms because they are safe for patients with small intestinal bacterial overgrowth and are more likely to colonize the G.I. tract.
• Prebiotics: a good formula would include arabinogalactan, beta-glucan, inulin, and oligofructose. Prebiotics may not be suitable for everyone with digestive disorders (especially those with SIBO); please see the bonus chapter for details.

Chris’s Preferred Products & Dosages:

• Betaine HCL/Pepsin from Thorne. Contains 650 mg of betaine HCL per capsule. Take 1-2 capsules with each meal. HCL is contraindicated if you have an ulcer or are currently taking NSAIDs.
• Super Enzymes from Now. Contains digestive enzymes and nutrients that support liver/gall bladder function. Therapeutic dose is 2 capsules three times daily with meals. Maintenance dose is 1 capsule three times daily with meals.
• Prescript Assist from Magnetic Clay. Soil-based organisms combined with a fulvic-acid-based prebiotic. Dosage is 1 capsule a day for the first 7 days, followed by 2 capsules a day for 30–90 days (until desired results are obtained), and then 1 capsule a day thereafter.
• GI Renew from Chris Kresser. Contains a synergistic blend of nutrients to support the gut barrier. Dosages is 7 capsules a day in divided doses.

Suggested supplement bundle:

I’ve created a discounted bundle of the supplements above that I recommend for digestive disorders, which you can learn more about and purchase here.

DIABETES AND OTHER BLOOD SUGAR DISORDERS

General Recommendations:

• Chromium: 100–300 mcg/d in chromium chelate form. (Note that some research suggests that chromium picolinate, a popular form of chromium, may cause DNA damage at high doses.)
• Alpha-lipoic acid: 200–400 mg/d.
• Magnesium: 300–500 mg/d in glycinate form.
• EGCG (green tea leaf extract): 200–300 mg/d.
• Gymnema sylvestre: 200–400 mg/d.
• Banaba leaf extract: 40–60 mg/d.
• Prebiotics: a good formula would include arabinogalactan, beta-glucan, inulin, and oligofructose.
• Probiotics: I prefer soil-based organisms because of their superior tolerability and colonization of the G.I. tract.
• Nutrients to support adrenal function: poor blood sugar control is often linked to low cortisol, high cortisol, or disruption in the normal diurnal rhythm of cortisol production. Supporting the adrenal system can help regulate blood sugar.

Chris’s Preferred Products & Dosages:

• Metabolic Synergy by Designs for Health. Helps support healthy glucose and insulin levels. Dosage is six capsules per day, two with each meal, or as directed by your healthcare practitioner.
• GlucoSupreme by Designs for Health. Supports healthy blood sugar with the use of cinnamon, corosolic acid from banaba, isoflavones from kudzu, and ginsenosides from ginseng. Dosage is two capsules two times daily with meals, or as directed by your healthcare practitioner.
• Prescript Assist from Magnetic Clay. Soil-based organisms combined with a fulvic-acid-based prebiotic. Dosage is 1 capsule a day for the first 7 days, followed by 2 capsules a day for 30–90 days (until desired results are obtained), and then 1 capsule a day thereafter.
• Prebiogen from Chris Kresser. A synergistic blend of arabinogalactan, beta-glucan, inulin, and oligofructose. Take 1 capsule a day.
• Stress Manager from Herb Pharm. A potent formula of adaptogenic botanicals that supports healthy adrenal function and regulates the stress response. Dosage is up to 40 drops in 2 oz. of water or juice, three or four times per day. Best taken between meals.

Suggested supplement bundle:

I’ve created a discounted bundle of the supplements above that I recommend for diabetes and other blood sugar disorders, which you can learn more about and purchase here.

ANXIETY, DEPRESSION AND COGNITIVE DISORDERS

General Recommendations:

• General brain support
• Vitamin B12: 800 mcg–5 mg/d, depending on the severity of B12 deficiency, in methylcobalamin form. Sublingual delivery is the most effective.
• DHA: 800–1,200 mg/d. For cognitive and mood disorders, I suggests supplements with a significantly higher dose of DHA than EPA.

Cognitive support (memory loss, difficulty concentrating, etc.)

• Acetyl L-carnitine: 1,000–2,000 mg/d in divided doses.
• Phosphatidylserine: 100–300 mg/d in divided doses.
• Bacopa: 200–600 mg/d in divided doses.
• Curcumin: 400–600 mg/d.

Mood support

• 5-HTP: 50–200 mg/d. 5-HTP should not be taken concurrently with antidepressant medication without supervision by your physician.
• St. John’s Wort: 300 mg three times a day. See the bonus chapter on anxiety, depression and cognitive disorders for important contraindications.
• SAMe: 400–1,600 mg/d. Start at the lower end of the dose range and increase slowly over a few weeks. SAMe should not be taken by people with biopolar disorder, because some reports suggests it may increase anxiety and mania in a subgroup of people with this condition.

Anti-anxiety

• Valerian root: 400 mg/d in divided doses. Be aware that valerian has a sedative effect, so exercise caution with higher doses.
• Passion flower extract: 200–300 mg/d.
• L-Theanine: 100–200 mg/d.

Chris’s Preferred Products & Dosages:

• Methyl B12 by Jarrow Formulas. A potent, sublingual form of active B12 (methylcobalamin). Start with 1 lozenge per day and increase to up to 5 lozenges per day for desired effect.
• Methyl-Guard by Thorne. Contains nutrients that support healthy B12 metabolism and methylation. Dosage is 1 capsule twice a day.
• ProDHA by Nordic Naturals. Each serving contains 900 mg of DHA, and only 180 mg of EPA. Dosage is 2 capsules a day with food.
• Memory Pro by Pure Encapsulations. A blend of nutrients that support cognition, memory and mental clarity. Dosage is 3 capsules once or twice daily with meals.
• GABA Ease by Vitanica. Contains nutrients and botanicals that calm nervous tension and anxiety. Dosage is 2 capsules once or twice daily with meals.
• SAMe by Jarrow Formulas. An enteric-coated form of SAMe made naturally by fermentation. Dosage is one 200 mg tablet once or twice daily with meals. See above for contraindications.
• Mood Enhancer by Wise Woman Herbals. A tincture containing St. John’s Wort, lemon balm, gotu kola and other botanicals that support and enhance mood. Dosage is 30–60 drops added to a small amount of water, three times daily.

Suggested supplement bundles:

I’ve created three discounted bundles of the supplements above, each addressing one of the following issues:

• Cognitive disorders (difficulty concentrating, memory, etc.)
• Anxiety
• Depression

Click here to learn more about them and purchase.

THYROID DISORDERS

General Recommendations:

• Iodine: please see the bonus chapter on thyroid disorders for more information and dosage instructions.
• Selenium: 200 mcg/d in selenomethionine form.
• Vitamin D: dosage will depend on many factors, including your current 25D level, sun exposure, diet, health status and place of residence. See the bonus chapter on supplementation for more information.
• Zinc: 15–30 mg/d as zinc amino acid chelate, picolinate or glycinate.
• Glutathione: 450 mg/d in liposomal form. Recommended for those with autoimmune thyroid disease (e.g. Hashimoto’s, Graves’, Ord’s).
• Ashwagandha: 500–1,000 mg/d in divided doses.
• Thyroid glandulars: see the bonus chapter on thyroid disorders for important cautions and dosage instructions.
• Bugleweed*: 30-40 drops two to four times daily; only recommended for patients with hyperthyroidism.
• L-carnitine*: 2–4 g/d; only recommended for patients with hyperthyroidism.
• Important note: hyperthyroidism is a serious and potentially life-threatening medical condition. Discuss these natural approaches with your physician before trying them, and do not stop your medication without the express permission of your physician.

Chris’s Preferred Products & Dosages:

• Kelp Tablets from NOW. See the bonus chapter on thyroid disorders for dosage instructions.
• Selenium by Pure Encapsulations. Selenomethionine form. Dosage is 1 capsule a day with food.
• Zinc from Nature’s Way. Each capsule contains 30 mg of zinc in amino acid chelate form. Dosage is 1 capsule a day with food.
• Liposomal Glutathione from Seeking Health. A liposomal form of glutathione (GSH), which is highly absorbable and effective. Take one teaspoon per day on an empty stomach.
• Bugleweed from Herb Pharm. Dosage is 30–40 drops in water three times a day with meals.
• L-carnitine from Jarrow Formulas. Dosage is 4–8 capsules a day on empty stomach.

Suggested supplement bundles:

I’ve created discounted bundles of the supplements above for hypothyroidism and hyperthyroidism. Learn more about the hypothyroidism and hyperthyroidism bundles and purchase.

AUTOIMMUNE DISEASE

General Recommendations:

• Vitamin D: I recommend people with autoimmune disease keep their serum 25D levels at the higher end of my recommended range of 25–50 ng/mL, i.e. somewhere between 40–50 ng/mL. See Chapter Sixteen in the book and the bonus chapter on supplementation for more information on how to do this.
• Glutathione: 450 mg/d in liposomal form.
• Curcumin: 600 mg once or twice daily, preferably in water-soluble, nano-particle form.
• EPA and DHA: though I prefer that you meet your EPA and DHA needs by eating cold-water, fatty fish, I realize that’s not always possible. If you’re taking cod liver oil, as I suggested in Chapter Eighteen, that does contain a moderate amount of both EPA and DHA. Some may benefit from additional EPA and DHA, which can be obtained by taking one gram per day of a high-quality fish oil.
• Probiotics: soil-based organisms may be particularly helpful for those with autoimmune disease. They were ubiquitous in our environment until very recently, and modern research inicates they have a regulatory effect on our immune system.
• Prebiotics: studies suggest that 75–80 percent of our immune system is in our gut. Prebiotics selectively stimulate the growth of beneficial gut bacteria, which support immune health.

Chris’s Preferred Products & Dosages:

• Liposomal Glutathione from Seeking Health. A liposomal form of glutathione (GSH), which is highly absorbable and effective. Take one teaspoon per day on an empty stomach.
• Liposomal Vitamin C from Seeking Health. A liposomal form of vitamin C that is more bioavailable than standard vitamin C preparations. Dosage: 1 tsp per day on an empty stomach.
• Longvida Optimized Curcumin from VRP. A highly bioavailable form of curcumin that is better absorbed than standard curcumin preparations. Take 1 twice a day on an empty stomach.
• Prescript Assist from Magnetic Clay. Soil-based organisms combined with a fulvic-acid-based prebiotic. Dosage is 1 capsule a day for the first 7 days, followed by 2 capsules a day for 30–90 days (until desired results are obtained), and then 1 capsule a day thereafter.

Suggested supplement bundle:

I’ve created a discounted bundle of the supplements above that I recommend for autoimmune disease, which you can learn more about and purchase here.

ADRENAL FATIGUE SYNDROME

General Recommendations:

• Pantethine: 450 mg twice daily with food.
• Vitamin C: 1–2 tsps once or twice daily, in liposomal form, depending on severity of adrenal fatigue.
• Adaptogenic herbs: these include Ashwagandha, Siberian ginseng (eleutherococcus), rhodiola, holy basil leaf, schisandra, and wild oats seed.
• Nutrients to regulate blood sugar: there is a close relationship between the adrenals and blood sugar, and most patients with adrenal fatigue also have poor blood sugar regulation. Chromium, alpha lipoic acid, gymnema sylvestre, and other nutrients mentioned above in the section on blood sugar disorders can be helpful in supporting proper adrenal function.
• Adrenal glandulars and hormones: as mentioned in the bonus chapter on adrenal fatigue syndrome, adrenal glandulars and hormones are best used under the supervision of a health care practitioner.

Chris’s Preferred Products & Dosages:

• Pantethine from Jarrow Formulas. A high-potency form of pantothenic acid. Take 1 capsule twice daily with food.
• Liposomal C from Seeking Health. A liposomal form of vitamin C that is more bioavailable than standard vitamin C preparations. Dosage: 1 tsp per day on an empty stomach.
• Stress Manager from Herb Pharm. A potent formula of adaptogenic botanicals that supports healthy adrenal function and regulates the stress response. Dosage is up to 40 drops in 2 oz. of water or juice, three or four times per day. Best taken between meals.
• Metabolic Synergy by Designs for Health. Helps support healthy glucose and insulin levels. Dosage is six capsules per day, two with each meal, or as directed by your healthcare practitioner.
• GlucoSupreme by Designs for Health. Supports healthy blood sugar with the use of cinnamon, corosolic acid from banaba, isoflavones from kudzu, and ginsenosides from ginseng. Dosage is two capsules two times daily with meals, or as directed by your healthcare practitioner.

Suggested supplement bundle:

I’ve created a discounted bundle of the supplements above that I recommend for adrenal fatigue syndrome, which you can learn more about and purchase here.

ACNE, ECZEMA, PSORIASIS AND OTHER SKIN CONDITIONS

General Recommendations:

• Vitamins A, D, and K2: the easiest way to obtain these is by taking cod liver oil and butter oil. I recommend Extra Virgin Cod Liver Oil (EVCLO). Dosage is 1 tsp a day.
• Quercetin and bromelain: 1,600–2,400 mg/ of quercetin and 200–400 mg/d of bromelain, taken in divided doses with meals.
• Vitamin C: 2–3 tsps per day in liposomal form.
• Nutrients to support proper methylation: as I described in the bonus chapter on skin conditions, histamine intolerance is associated with poor methylation. To improve methylation, take 400–1,200 mg/d of active folate (5-MTHF), 400–1,200 mg/d of active B12 (methylcobalamin), 600–1,800 mg/d of trimethylglycine (aka betaine anhydrous), and 5–20 mg of active B6 (pyridoxal 5’–phosphate, aka P5P).
• Probiotics: not all probiotics are suitable for skin conditions, especially if histamine intolerance is present. I have found that soil-based organisms and specific histamine-degrading species like Bifidobacterium infantis, Bifidobacterium longum, and Lactobacillus plantarum are most beneficial. Dosage varies depending on the product.
• Prebiotics: Taking prebiotics is the most effective way of increasing the levels of bifidobacteria already in your gut. Since bifidobacteria is histamine-degrading overall, prebiotics can be an effective treatment for histamine intolerance.
• Diamine oxidase: This is only required for those with severe histamine intolerance, or for those with mild to moderate histamine intolerance that wish to enjoy histamine-containing foods on occasion; dosage is 4,000–10,000 HDU before eating the histamine-containing food.

Chris’s Preferred Products & Dosages:

• Extra Virgin Cod Liver Oil (EVCLO). The highest quality cod liver oil currently on the market. Dosage is 1 teaspoon a day.
• Quercetin and Bromelain from NOW. Dosage is 1 capsule three times daily with food.
• Liposomal C from Seeking Health. A liposomal form of vitamin C that is more bioavailable than standard vitamin C preparations. Dosage: 1 tsp per day on an empty stomach.
• Prescript Assist from Magnetic Clay. Soil-based organisms combined with a fulvic-acid-based prebiotic. Dosage is 1 capsule a day for the first 7 days, followed by 2 capsules a day for 30–90 days (until desired results are obtained), and then 1 capsule a day thereafter.
• Methyl-Guard from Thorne. Contains the active forms of B12, folate, and B6, as well as trimethylglycine, to support proper methylation and reduce histamine intolerance. Dosage is 1 capsule one to three times daily. Start with the lower dose and build up slowly over time to the full dose.
• Prebiogen from ChrisKresser.com. A synergistic blend of arabinogalactan, beta-glucan, inulin, and oligofructose Take 1 capsule a day. (If you experience gas or bloating at this dose, start with 1/4–1/2 capsule per day and increase slowly to 1 capsule a day.)
• Histame from Naturally Vitamins. Histame contains diamine oxidase (DAO).

Suggested supplement bundle:

I’ve created a discounted bundle with the four most important supplements above that I recommend for skin conditions. You may also wish to take the Extra Virgin Cod Liver Oil, Prebiogen, and Histame for optimal results, which you can learn more about and purchase here.